City
Epaper

Autism symptoms' severity varies greatly among twins

By IANS | Updated: December 30, 2019 13:00 IST

Identical twins with autism spectrum disorder (ASD) often experience large differences in symptom severity even though they share the same DNA, researchers from Washington University have found.

Open in App

The findings, published in the journal Behaviour Genetics, suggest that identifying the causes of this variability may inform the treatment of ASD-related symptoms.

Autism spectrum disorder is a developmental disorder that affects how a person behaves, interacts with others and learns.

Previous studies have found that when one identical twin has autism spectrum disorder, spectrum disorder chances are extremely likely that the other twin has it, too.

For the findings, the researchers analysed data from three previous studies comprising a total of 366 identical twin pairs with and without ASD.

The severity of autism traits and symptoms in the twins was measured by a clinician's assessment or by parents' ratings on a standardised questionnaire.

Some cases were diagnosed by both methods. The researchers determined a 96 per cent chance that if one twin has ASD, the other has it, too.

However, symptom scores varied greatly between twins diagnosed with ASD.

The researchers estimated that genetic factors contributed to only nine per cent of the cause of trait variation among these twins.

In contrast, among pairs of identical twins without ASD, the scores for traits were very similar.

According to the study, the authors do not know the reasons for differences in symptom severity, but they rule out genetic and most environmental causes because the twins share the same DNA and were raised in the same environment.

Additional studies are needed to determine the cause, the researchers said.

( With inputs from IANS )

Open in App

Related Stories

BusinessCoffee exports from India have doubled in recent years: Commerce Secretary

InternationalPoJK, Gilgit-Baltistan activists highlight Pakistan's human rights violations at UNHRC session in Geneva

NationalBaijayant Panda to chair select committee on Insolvency and Bankruptcy Code Bill

NationalCoffee exports from India have doubled in recent years: Commerce Secretary

MumbaiMumbai Tops India in Financial Crimes in 2023, NCRB Report Shows

स्वास्थ्य Realted Stories

HealthUS government shuts down in political standoff with dim prospects of early deal 

HealthDelhi HC quashes FIR against man accused of assaulting doctor, orders community service at same hospital

HealthCentre launches adoption awareness campaign for children with special needs

HealthDPIIT, Thermo Fisher Scientific tie up to boost India’s biotech startup ecosystem

Health‘Cough syrup not contaminated’: MP Dy CM on death of six children in Chhindwara