Israeli scientists say they have managed to successfully reverse the biological aging process using only oxygen. Recent research led by Tel Aviv University’s Prof. Shai Efrati, together with a team from Shamir Medical Center, found that when healthy adults over the age of 64 were placed in a pressurized chamber and given pure oxygen for 90 minutes a day, five days a week for three months, not only was the aging process delayed - it was actually reversed.
Specifically, the study, which is published in the peer-reviewed journal Aging, focused on whether the process could reverse two key indicators of biological aging: the shortening of DNA telomeres and the accumulation of resultant senescent cells.A telomere is the end of a chromosome. Telomeres are made of repetitive sequences of non-coding DNA that serve as bumpers to protect the chromosome from damage during replication. Every time replication happens, these bumpers take a hit, making them shorter and shorter.
Once the telomere reaches a certain length, the cell cannot replicate anymore, which leads to senescent cells: aging, malfunctioning cells that ultimately lead to cognitive or other age-related disabilities and even diseases, such as cancer.Some 35 adults over the age of 64 were involved in the study and were administered hyperbaric oxygen therapy (HBOT) utilizing 100% oxygen in an environmental pressure higher than one absolute atmospheres to enhance the amount of oxygen dissolved in the body's tissues. Every 20 minutes, the participants were asked to remove their masks for five minutes, bringing their oxygen back to normal levels. However, during this period, researchers saw that fluctuations in the free oxygen concentration were interpreted at the cellular level as a lack of oxygen – rather than interpreting the absolute level of oxygen.