He said the report by the country's corruption watchdog was "fundamentally and irretrievably flawed", the BBC reported on Sunday.
Speaking to reporters, he also said it was appropriate for courts to make an impartial judgment on the matter.
Ramaphosa's supporters say the allegations are politically motivated.
The report by Public Protector Busisiwe Mkhwebane was released on Friday. It accused President Ramaphosa of misleading parliament, it suggested that he had potentially committed a money laundering offence.
Last year, Ramaphosa told parliament that he had not received election campaign donations from a controversial company during his bid to lead the ANC.
It later emerged that was not true. Ramaphosa apologised, and said he had been misinformed.
The allegations against the President are seen by many as a battle for control of the ANC, and South Africa itself.
Party factions have become more entrenched since President Jacob Zuma, 77, was forced to resign in February 2018 amid widespread allegations of corruption, which he denies.
He was replaced by his then-deputy, Ramaphosa, who promised to tackle corruption and described Zuma's nine years in office as "wasted".
Critics of Mkhwebane say she has become a participant in a fight-back by allies of former President Zuma.
The battles are likely to play out in South Africa's courts, which have remained largely independent.
( With inputs from IANS )