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The Indus River is one of the longest rivers in Asia. Originating in the Tibetan Plateau in the vicinity of Lake Manasarovar, the river runs a course through the Ladakh region of Jammu and Kashmir, India, towards the Gilgit-Baltistan region of Pakistan and the Hindukush ranges, and then flows in a southerly direction along the entire length of Pakistan to merge into the Arabian Sea near the port city of Karachi in Sindh.