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Madhira is a municipality in Khammam district of the Indian state of Telangana. It is located in Madhira mandal of Khammam division.It is located about 230 kilometres east of the state capital, Hyderabad, 53 kilometers from Khammam, 130 kilomkilometresmi from bhadrachalam and also it is located about 77 kilometers North of the Andhra Pradesh state capital, Amaravathi.