City
Epaper

Targeted therapies, diagnostics remain concern for severe asthma: Report

By IANS | Updated: December 27, 2024 13:25 IST

New Delhi, Dec 27 There is an urgent need for improved diagnostic tools and targeted therapies to address ...

Open in App

New Delhi, Dec 27 There is an urgent need for improved diagnostic tools and targeted therapies to address the gap in care for patients with severe asthma, specifically for those with T-helper cell type 2 (T2)-low asthma, a subtype lacking typical inflammatory biomarkers, according to a report on Friday.

T2-low asthma presents unique challenges due to the absence of eosinophils and immunoglobulin E (IgE), which complicates both diagnosis and treatment. And treatments currently available are primarily focused on eosinophilic and allergic inflammation. This leaves patients with non-eosinophilic or neutrophilic asthma without adequate options.

The report by GlobalData, a data and analytics company, showed that while T2-high asthma has benefitted from targeted biologic treatments, T2-low asthma remains largely underserved.

“The current treatment landscape for severe asthma has made significant strides, particularly for T2-high asthma. However, T2-low asthma remains largely under-researched and under-treated. There is an urgent need for both reliable biomarkers and therapies targeting this neglected subset of asthma patients,” said Sravani Meka, Senior Pharmaceutical Analyst at GlobalData.

While Meka lauded emerging therapies, she called for more research and development to help people with T2-high asthma. She also highlighted the need to develop new diagnostic tools that help distinguish T2-low asthma from other forms of asthma. Often people with T2-high asthma remain undiagnosed or misdiagnosed, resulting in delayed and inadequate treatment.

The report noted that despite the availability of biologics, many patients struggle with inhaler technique, high medication costs, and inconsistent use, resulting in poor asthma control, and preventing optimal treatment outcomes.

The report urged for addressing patient education on inhaler use and improving access to treatments for enhancing asthma control.

“To truly address the needs of T2-low asthma patients, there must be a concerted effort to improve diagnostics, develop targeted treatments, and ensure better access to care. Only then can we achieve significant improvements in asthma management for all patients, regardless of their asthma subtype,” Meka said.

Disclaimer: This post has been auto-published from an agency feed without any modifications to the text and has not been reviewed by an editor

Open in App

Related Stories

InternationalTaiwan detects Chinese military activity near its territory

NationalHeavy rain, thunderstorms bring relief from scorching heat in Delhi-NCR

NationalKarnataka Crime: Suhas Shetty, Hindu Activist, Brutally Hacked to Death in Mangaluru

NationalKhalistani terrorist Pannun posts provocative message for Indian Sikh Army soldiers after Pahalgam attack

International"PM Modi has our full support": US State Dept spokesperson Tammy Bruce

Technology Realted Stories

TechnologyZoho CEO Sridhar Vembu has no ‘confidence in tech’, shelves $700 million chip plan

TechnologyYouTube commits Rs 850 crore to power India’s ‘Creator Nation’: CEO Neal Mohan

TechnologyApple clocks 28 pc growth in iPhone shipments in India: Industry data

TechnologyNHRC asks 11 states to boost measures to prevent heat-related deaths

TechnologyNRAI and ONDC refute speculative reports, reaffirm strong partnership