University of leicester, Public university in Leicester, England

A new international genomics research led by the University of Leicester used artificial intelligence (AI) to study an aggressive form of cancer, which could be helpful in improving patient outcomes.Mesothelioma is caused by breathing asbestos particles and most commonly occurs in the linings of the lungs or abdomen. Currently, only seven per cent of people survive five years after diagnosis, with a prognosis averaging 12 to 18 months.New research undertaken by the Leicester Mesothelioma Research Programme has now revealed, using AI analysis of DNA-sequenced mesotheliomas, that they evolve along similar or repeated paths between individuals. These paths predict the aggressiveness and possible therapy of this otherwise incurable cancer.Professor Dean Fennell, Chair of Thoracic Medical Oncology at the University of Leicester and Director of the Leicester Mesothelioma Research Programme, said: "It has long been appreciated that asbestos causes mesothelioma, however, how this occurs remains a mystery.""Using AI to interrogate genomic 'big data', this initial work shows us that mesotheliomas follow ordered paths of mutations during development and that these so-called trajectories predict not only how long a patient may survive, but also how to better treat cancer - something Leicester aims to lead on internationally through clinical trial initiatives."While the use of asbestos is now outlawed - and stringent regulations in place on its removal - each year around 25 people are diagnosed with mesothelioma in Leicestershire and 190 are diagnosed in the East Midlands. Cases of mesothelioma in the UK have increased by 61 per cent since the early 1990s.Until very recently, chemotherapy was the only licenced choice for patients with mesothelioma. However, treatment options start to become limited once people stop responding to their treatment.Professor Fennell in collaboration with the University of Southampton recently made a major breakthrough in treating the disease by demonstrating that the use of an immunotherapy drug called nivolumab increased survival and stabilised the disease for patients. This was the first-ever trial to demonstrate improved survival in patients with relapsed mesothelioma.( With inputs from ANI )Disclaimer: This post has been auto-published from an agency feed without any modifications to the text and has not been reviewed by an editor

University Of LeicesterFOLLOW

University of leicester, Latest News

Robert Lewandowski has been ruled out of the 2022 World Cup qualifying match against England due to a knee injury, the Polish FA announced on Monday. ...

London, March 29 England on Monday further eased its coronavirus contact restrictions to allow for larger outdoor meet-ups ... ...

London, March 29 Britons should not "squander the gains" made against the coronavirus pandemic in recent months, Medical ... ...

London, March 29 England have made it two wins out of two in their World Cup qualifying ... ...

Pacer Shardul Thakur has said that it is important to take wickets at regular intervals against England as the Three Lions have a very deep batting lineup and they can hurt if there are wickets in hand. ...

England opening batsman Jonny Bairstow on Sunday said that he will take the confidence from the white-ball series against India into the upcoming Indian Premier League (IPL) for the SunRisers Hyderabad. ...

After registering a seven-run win in the third ODI against England here at the Maharashtra Cricket Association Stadium in Pune, India pacer Bhuvneshwar Kumar on Sunday said that he wants to play the longest format of the game, so his workload managem ...

A new international genomics research led by the University of Leicester used artificial intelligence (AI) to study an aggressive form of cancer, which could be helpful in improving patient outcomes. ...