University of salento, University in Lecce, Italy

Rome, Nov 8 People with kidney failure who are on dialysis or who have received a kidney transplant face a higher risk of dying from Covid-19 due to differences in their immune system, finds a study.The team from Universita di Brescia-ASST Spedali Civili di Brescia, Italy, found that these individuals have profound immune system-related differences compared with people with normal kidney function. These differences are further amplified by SARS-CoV-2 infection.The study included 32 patients who were on dialysis or who received a kidney transplant and were hospitalised for Covid-19, as well as 12 dialysis or transplant patients without Covid-19 and 10 healthy controls.Patients with a severe Covid-19 course were older and showed lower counts of immune cells called lymphocytes and monocytes, compared with patients with a benign disease course.Patients without Covid-19 had lower numbers of all major immune cell subsets compared with healthy patients, and these numbers were further reduced in patients with Covid-19, especially in patients with a severe disease course."Although dialysis and kidney transplant patients are inherently heterogeneous groups, the immunological abnormalities during Covid-19 are similar across the two cohorts, with the exception of more pronounced defects in innate immunity and a dampened antibody response in kidney transplant patients," said lead author Stefania Affatato, from the varsity.The findings will be presented online at ASN Kidney Week 2021 November 4-7.People suffering with severe cases of Covid-19 have shown signs of kidney damage, even those who had no underlying kidney problems before they were infected with the coronavirus.Early reports say that up to 30 per cent of patients hospitalised with Covid-19 in China and New York developed moderate or severe kidney injury, while reports from doctors in New York said the percentage could be higher.Signs of kidney problems in patients with Covid-19 include high levels of protein in the urine and abnormal blood work. The kidneys' essential functions have an impact on the heart, lungs and other systems, leading to a serious, and even fatal course of the disease.Disclaimer: This post has been auto-published from an agency feed without any modifications to the text and has not been reviewed by an editor

University Of SalentoFOLLOW

University of salento, Latest News

Canadian rocker Bryan Adams has shared a new update from Milan, Italy where he was taken to the hospital after testing positive for COVID upon arrival at the Milan Malpensa airport on Thursday. ...

Singer and guitarist Bryan Adams has posted an update today from the hospital in Milan, Italy where he was taken after testing COVID positive for the second time in a month, upon arrival at the Milan Malpensa airport on Thursday. ...

Either Italy or Portugal will fail to qualify for the 2022 FIFA World Cup Qatar as the two sides were drawn in the same qualifying playoffs. ...

Rome, Nov 26 French President Emmanuel Macron and Italian Prime Minister Mario Draghi met to work toward finalising ... ...

Rome, Nov 19 A top Italian health official said there were no plans to tighten coronavirus restrictions in ... ...

Kochi, Nov 11 For the second time since it began hearing the ongoing Crime Branch probe in the ... ...

Rome, Nov 9 Italy's Covid-19 situation is stable under the current rules despite the ongoing fourth wave of ... ...

Rome, Nov 8 People with kidney failure who are on dialysis or who have received a kidney transplant ... ...