1 / 6Heart disease continues to be the leading cause of death in both men and women worldwide. Contrast to what you may see in a movie, the signs of a heart attack can be hard to miss. Though symptoms like chest tightness and upper body pain are more obvious, heart attacks present a host of symptoms that can be easily mistaken for another ailment (think nausea, heartburn, and fatigue).The very first symptom of a heart attack listed by the American Heart Association is 'uncomfortable pressure, squeezing, fullness, or pain in the center of your chest.' This discomfort may come in waves lasting more than a few minutes at a time.2 / 6If you have congestive heart failure, one or both of your heart's lower chambers lose their ability to pump blood effectively. As a result, blood can back up in your legs, ankles and feet, causing edema.3 / 6Feeling worn out after a sleepless night or a stressful day is normal. But women can feel fatigued a month out before having a heart attack, Harvard Health Publishing reports. According to the National Heart, Blood, and Lung Institute, this sign is especially prominent in women.4 / 6According to Stoney Brook Medicine, gastric symptoms like a queasy stomach, vomiting, or belching develop when the heart and other areas of the body aren't receiving enough blood supply. It can be misjudged as acid reflux or heartburn, so it's important to reach out to your doctor, especially if you're having other heart attack symptoms.5 / 6Prolonged exposure to cold or related symptoms also indicates a heart attack. Do not ignore this sign at all and consult a doctor immediately.6 / 6Fatigue: Cholesterol causes the arteries to constrict and the heart has to work harder. As a result, you soon start feeling tired.