1 / 7Excessive use of sanitizer can increase contact with irritants and allergens may increase the risk of hand dermatitis or 'eczema.' 2 / 7Frequent use of sanitizer can cause skin irritation, or dry out the skin. If you have sensitive skin, the effects can be worse. The drying out is caused by alcohol.3 / 7There are some non-alcohol-based hand sanitizers that consist of an antibiotic compound called triclosan or triclocarban. Several research studies have reported that triclosan is a health hazard as its overuse has negative effects on fertility and fetal development. 4 / 7Triclosan present in a hand sanitizer also causes hormone problems. This causes the bacteria to adapt to its antimicrobial properties, which creates more antibiotic-resistant strains. 5 / 7Triclosan also weakens the human immune function. The weakened immune system makes people more susceptible to allergies,' says Dr. Norris.6 / 7A hand sanitizer that has too much fragrance could be loaded with toxic chemicals like phthalates and parabens. Phthalates are endocrine disruptors that can affect human body development and reproduction. 7 / 7Overuse of alcohol-based hand sanitizers to safeguard against the germs and infection-causing pathogens could inversely increase the risk of infection via skin disorders.